Predictive Value of Serum Interleukins in Children with Idiopathic Nephrotic Syndrome

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Serum interleukins and urinary microglobulin in children with idiopathic nephrotic syndrome.

We studied 60 children affected with idiopathic nephrotic syndrome (INS) plus 20 age and sex matched controls. The children with INS were divided into 3 groups of 20: first presentation, remission and relapse. A complete blood picture and complete urinalysis were done. Serum interleukin (IL)-1beta, IL-6, tumour necrosis factor (TNF) and quantitative urinary beta-2-microglobulin (beta-2-m) excre...

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Relationship of Renal Cortical Echogenicity in Renal Ultrasonography with Course of Disease in Children with Idiopathic Nephrotic Syndrome

Background It is important to find a predictor for the course of Idiopathic Nephrotic Syndrome for better planning of treatment. Renal cortical echogenicity in ultrasonography has been postulated as a marker for the course of renal disease. The present study aimed at evaluating the relationship between renal cortical echogenicity and the course...

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Idiopathic nephrotic syndrome in Iranian children.

Of 231 children with nephrotic syndrome, 87% were steroid sensitive and 13% steroid resistant. Of patients with steroid sensitive nephrotic syndrome, 38.8% were non-relapsers, 34.8% frequent relapsers and 26.4% infrequent relapsers. Among those with steroid resistant nephrotic syndrome, 37.5% had focal segmental glomerulosclerosis with a high mortality rate of 44%

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Carotid artery function in children with idiopathic nephrotic syndrome.

BACKGROUND Nephrotic patients are prone to atherosclerosis in consequence of frequent exposures to hyperlipidemia, hypertension, and immunosuppressive drugs. OBJECTIVES We studied the carotid parameters as early indicators of atherosclerosis in children with nephrotic syndrome. METHODS Between 2008 and 2011, 51 children with history of nephrotic syndrome enrolled in the study. The inclusion...

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Children with idiopathic nephrotic syndrome (INS) may be at risk for metabolic bone disease (MBD) because of biochemical derangements caused by the renal disease, as well as the corticosteroid effects on bone. We studied 70 children with INS for clinical, biochemical, and radiological evidence of MBD. These patients were divided into two groups: 55 frequent relapsers (FR; group I), and 15 infre...

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ژورنال

عنوان ژورنال: Iranian Journal of Allergy, Asthma and Immunology

سال: 2020

ISSN: 1735-5249,1735-1502

DOI: 10.18502/ijaai.v19i6.4932